ceesdekker No Further a Mystery
ceesdekker No Further a Mystery
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2009, discovery of a whole new phenotype for germs in slim nanofluidic slits; and 1st detection of community protein buildings together DNA using strong-state nanopores
Our group studies bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin construction, and spatial Manage.
Like a individual, I contain the biblical assignment to discover and use almost everything in generation for the benefit of my neighbour. I usually do not practical experience any conflict concerning faith and science. On the contrary, my faith stimulates me to try and do science, to generally be open-minded on the planet.’
I can hardly envision how I, as being a geneticist, would have the ability to discover essential physics, not to mention compete at the very best. How did you go about it?
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever layout in 2005. (nl)
Instance (three) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim from the pore is highlighted in pink, and also a 3D rendering from the movement on the DNA rod is displayed.
Length Charge of particular person carbon nanotubes by nanostructuring Along with the scanning tunneling microscope
Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim on the pore is highlighted in red, and also a 3D rendering from the movement from the DNA rod is shown.
What if, instead of working with standard major-down silicon electronics, transistors may be built from The underside up ceesdekker utilizing one organic molecules as being the switching components? This concept, which became The idea of today’s subject of molecular electronics, first emerged while in the 1970s.
Incredibly cool, but that wasn’t seriously where my curiosity lay. I planned to pioneer And that i had the feeling which was now not feasible, since the most attention-grabbing fundamental insights had previously been uncovered. But my industry had produced quite a few exciting new resources to measure particular person molecules. I made a decision that I desired to use this to biology, to take a look at it from the Actual physical point of view.’
Because 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. A lot more recently his exploration has focused on finding out chromatin structure and mobile division with bacteria on chip, when he is additionally seeking to in the end Establish synthetic cells from The underside up.
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2008, to start with observation of protein-coated DNA translocation through nanopores; fixed the origin of your electrophoretic drive on DNA in nanopores; found out an important velocity raise of microtubules in electric powered fields; uncovered an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid
2004, discovery of latest physics in translocation of DNA via nanopores; to start with experimental examine of ions conduction in nanofluidic channels; to start with electrochemistry with specific single-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; very first biophysics characterization of the mechanical Homes of double-stranded RNA; and first solitary-molecule analyze of DNA translocation by a restriction-modification enzyme.